BDBM50254711 CHEMBL443087::N-((1S,2R)-1-Benzyl-3-cyclopropylamino-2-hydroxy-propyl)-5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-N'-((R)-1-phenyl-ethyl)-isophthalamide

SMILES C[C@@H](NC(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CC1)N1CCCS1(=O)=O)c1ccccc1

InChI Key InChIKey=MBKQDBPGZVELFG-ZDERHKTGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254711   

TargetBeta-secretase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254711(CHEMBL443087 | N-((1S,2R)-1-Benzyl-3-cyclopropylam...)
Affinity DataIC50:  141nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254711(CHEMBL443087 | N-((1S,2R)-1-Benzyl-3-cyclopropylam...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed