BDBM50254911 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide::CHEMBL480411

SMILES CC(C)(C)NS(=O)(=O)c1ccc(cc1)-c1ccc2[nH]nc(N)c2c1

InChI Key InChIKey=KFJCXIOVAGJCKB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254911   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sgx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254911(4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesul...)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Sgx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254911(4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesul...)
Affinity DataIC50:  78nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair