BDBM50255049 5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazonomethyl}-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzoic acid::CHEMBL481969

SMILES OC(=O)c1cc(C=NNC(=O)CS(=O)(=O)c2ccc(Cl)cc2)c(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=LIPBUDUJYLHQGE-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50255049   

LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to ABLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to TRAK-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity to LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity to MAP3K9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to PKC beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to ECKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to MST2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255049(5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed