BDBM50255213 CHEMBL4068572

SMILES NC(=O)c1cnc(SC2CCCNC2)c2cc(sc12)-c1ccccc1

InChI Key InChIKey=YELZIMYSGBRSRC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255213   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50255213(CHEMBL4068572)
Affinity DataIC50: 56nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50255213(CHEMBL4068572)
Affinity DataEC50:  210nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of camptothecin-induced G2/M phase arrestMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details Article
PubMed
LigandPNGBDBM50255213(CHEMBL4068572)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details Article
PubMed