BDBM50255382 (S)-N-((1r,4S)-4-tert-butylcyclohexyl)-1-oxo-2,3-diphenyl-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL481609

SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)NC(=O)N1CCC2(CC1)[C@@H](N(C2=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=BVDKYCVYZYRHCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255382   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50255382((S)-N-((1r,4S)-4-tert-butylcyclohexyl)-1-oxo-2,3-d...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of PMA-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50255382((S)-N-((1r,4S)-4-tert-butylcyclohexyl)-1-oxo-2,3-d...)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed