BDBM50255422 4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)-N-(2-aminophenyl)benzamide::CHEMBL481805

SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nccc(n2)-c2cc[nH]n2)cc1

InChI Key InChIKey=IJFMLKFWTKPUEN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50255422   

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 320nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed