BDBM50255758 CHEMBL499218::ethyl 4-((S)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamido)-3-oxoazepane-1-carboxylate

SMILES CCOC(=O)N1CCCC(NC(=O)[C@H](CC(C)(C)F)N[C@@H](c2ccc(cc2)-c2ccc(cc2)S(C)(=O)=O)C(F)(F)F)C(=O)C1

InChI Key InChIKey=WILVMDVKNXRXEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255758   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255758(ethyl 4-((S)-4-fluoro-4-methyl-2-((S)-2,2,2-triflu...)
Affinity DataIC50: 54nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed