BDBM50255964 CHEMBL4096822

SMILES CCC(=O)N1CC[C@@H](C1)N1C(=O)N(Cc2cnc(Nc3ccc(N4CCN(C)CC4)c(C)c3)nc12)c1cc(OC)ccc1F

InChI Key InChIKey=XNGPUTOLQIOMMI-DEOSSOPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255964   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50255964(CHEMBL4096822)
Affinity DataIC50:  362nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus using tyr4 peptide as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50255964(CHEMBL4096822)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus using tyr4 peptide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed