BDBM50256010 3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarbonyl)-1,2-dihydro-indol-3-ylidenemethyl]-1H-pyrrol-3-yl}-propionic acid::CHEMBL480356

SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C(=O)NNc2ccccc2)c(C)c1CCC(O)=O

InChI Key InChIKey=GCZQBFMPHLFNIO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50256010   

TargetPlatelet-derived growth factor receptor beta(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50256010(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50256010(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Affinity DataIC50: 70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50256010(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human FGFR1 expressed in insect cells by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50256010(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed