BDBM50256041 CHEMBL506414::N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)-c3cccs3)cc2Cl)c1

InChI Key InChIKey=PBIJKZCHYCDPPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256041   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256041(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(thioph...)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256041(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(thioph...)
Affinity DataIC50: 43nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed