BDBM50256110 CHEMBL480585::N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide

SMILES COc1cc(NC(=O)C2COc3ccccc3C2)ccc1-c1cn[nH]c1

InChI Key InChIKey=ALCYEYMJMMRBQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256110   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256110(N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-c...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256110(N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-c...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed