BDBM50256112 CHEMBL519101::N-(2-fluoro-4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide

SMILES Fc1cc(ccc1NC(=O)C1COc2ccccc2C1)-c1cn[nH]c1

InChI Key InChIKey=HVJWOVNRCTWQQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256112   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256112(N-(2-fluoro-4-(1H-pyrazol-4-yl)phenyl)chroman-3-ca...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256112(N-(2-fluoro-4-(1H-pyrazol-4-yl)phenyl)chroman-3-ca...)
Affinity DataIC50: 80nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed