BDBM50256114 CHEMBL481731::N-(5-fluoro-2-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide

SMILES COc1cc(-c2cn[nH]c2)c(F)cc1NC(=O)C1COc2ccccc2C1

InChI Key InChIKey=KFWHAIAFFYRAAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256114   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256114(N-(5-fluoro-2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256114(N-(5-fluoro-2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed