BDBM50256157 CHEMBL481894::N-((5-chloro-8-hydroxyquinolin-7-yl)(2-chlorophenyl)methyl)-2-phenoxyacetamide

SMILES Oc1c(cc(Cl)c2cccnc12)C(NC(=O)COc1ccccc1)c1ccccc1Cl

InChI Key InChIKey=WWYHGNBGETZJPI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256157   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50256157(N-((5-chloro-8-hydroxyquinolin-7-yl)(2-chloropheny...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50256157(N-((5-chloro-8-hydroxyquinolin-7-yl)(2-chloropheny...)
Affinity DataIC50: 350nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50256157(N-((5-chloro-8-hydroxyquinolin-7-yl)(2-chloropheny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ADAMTS4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50256157(N-((5-chloro-8-hydroxyquinolin-7-yl)(2-chloropheny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256157(N-((5-chloro-8-hydroxyquinolin-7-yl)(2-chloropheny...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of MMP13 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed