BDBM50256384 6-chloro-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide::CHEMBL482363

SMILES COc1cc(NC(=O)C2COc3ccc(Cl)cc3C2)ccc1-c1cn[nH]c1

InChI Key InChIKey=AHRBXUXOSXBPRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256384   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256384(6-chloro-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50256384(6-chloro-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 38nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed