BDBM50256779 CHEMBL451232::trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]methylamine Hydrochloride

SMILES NC[C@H]1C[C@@H]1c1ccc(F)cc1Cl

InChI Key InChIKey=ZKKSFFWCPNXRRU-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50256779   

Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataKi:  254nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]meth...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed