BDBM50256927 CHEMBL475796::N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenylamino)methyl)benzamide

SMILES Cc1ccc(NCc2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1nccc(n1)-c1cccnc1

InChI Key InChIKey=JLIZHCYTSUGKKN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50256927   

TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50256927(N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataIC50: 208nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50256927(N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataIC50: 208nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50256927(N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50256927(N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild-type c-Abl by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256927(N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PDGFRbeta by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256927(N-(2-aminophenyl)-4-((4-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of VEGFR2 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed