BDBM50257016 (4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid (3R)-2-oxo-1-[(4-oxo-pent-2-enylcarbamoyl)-methyl]-5-phenyl-2,3-dihydro-1Hbenzo[e][1,4]diazepin-3-ylmethyl ester::CHEMBL509518

SMILES CC(=O)CC=CNC(=O)CN1c2ccccc2C(=N[C@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)C1=O)c1ccccc1

InChI Key InChIKey=ZWAVSBHNASNYEB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50257016   

TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50257016((4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid ...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50257016((4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid ...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50257016((4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid ...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human cathepsin-B using Cbz-Phe-Arg-AMC as substrate by spectrofluorometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50257016((4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid ...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrate by spectrofluorometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed