BDBM50257088 CHEMBL4066784

SMILES C[C@H]1C[C@@H](C)CN(CCCNC(=O)C2CCN(Cc3nc(oc3C)-c3c(C)cccc3Cl)CC2)C1

InChI Key InChIKey=SHKOYYABTMCHBH-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50257088   

Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  415nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  443nMAssay Description:Displacement of [3H]Cimetidine from human H2 receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  575nMAssay Description:Displacement of [3H]Rauwolscine from human alpha2C receptor expressed in MDCK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]U69593 from KOR receptor (unknown origin) expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [3H]Nisoxetine from human NET receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]Rauwolscine from human alpha2A receptor expressed in MDCK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  1.75E+3nMAssay Description:Displacement of [3H]QNB from human M5 receptor expressed in CHO cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  1.81E+3nMAssay Description:Displacement of [3H]Pentazocine from guinea pig Sigma1 receptor after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50257088(CHEMBL4066784)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]Citalopram from human SERT receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed