BDBM50257118 CHEMBL475051::N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide

SMILES ONC(=O)c1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(s2)-c2cccnc2)c1

InChI Key InChIKey=CJXZQDNBKDLDLD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257118   

TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257118(N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamin...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257118(N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamin...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257118(N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamin...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of wild-type c-Abl by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257118(N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamin...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PDGFRbeta by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257118(N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamin...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of VEGFR2 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed