BDBM50257333 (+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hydrochloride::CHEMBL467736

SMILES NC[C@H]1C[C@@H]1c1ccccc1Br

InChI Key InChIKey=WYOKWGHFWKWDEZ-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50257333   

Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataEC50:  0.780nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataKi:  246nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataKi:  2.12E+3nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257333((+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]meth...)
Affinity DataKi:  3.82E+3nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed