BDBM50257335 CHEMBL492916::trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hydrochloride

SMILES NCC1CC1c1ccccc1Br

InChI Key InChIKey=WYOKWGHFWKWDEZ-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50257335   

Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataKi:  655nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataKi:  2.72E+3nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataKi:  2.73E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257335(trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hy...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed