BDBM50257512 (S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonamido)-3-(3-carbamimidoylphenyl)propanoyl)piperidin-4-yl)-N-methylbutanamide::CHEMBL444411::US8569313, 32

SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key InChIKey=HWNRARJHWWELBD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50257512   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512(US8569313, 32 | CHEMBL444411 | (S)-4-(1-(2-(3-(3-a...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512(US8569313, 32 | CHEMBL444411 | (S)-4-(1-(2-(3-(3-a...)
Affinity DataKi:  6.30nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetProthrombin(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512(US8569313, 32 | CHEMBL444411 | (S)-4-(1-(2-(3-(3-a...)
Affinity DataKi:  850nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512(US8569313, 32 | CHEMBL444411 | (S)-4-(1-(2-(3-(3-a...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512(US8569313, 32 | CHEMBL444411 | (S)-4-(1-(2-(3-(3-a...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512(US8569313, 32 | CHEMBL444411 | (S)-4-(1-(2-(3-(3-a...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed