BDBM50257638 CHEMBL493743::ethyl 4-(1-(4-aminopyridin-2-yl)-4-phenylpiperidine-4-carbonyl)piperazine-1-carboxylate

SMILES CCOC(=O)N1CCN(CC1)C(=O)C1(CCN(CC1)c1cc(N)ccn1)c1ccccc1

InChI Key InChIKey=RGSYANNBEVLWOT-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257638   

TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257638(ethyl 4-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by ALPHAscreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50257638(ethyl 4-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  169nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed