BDBM50257664 (S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-oxo-1-(piperazin-1-yl)propan-2-yl)sulfamoyl)phenyl)propanamide::CHEMBL493118::US8569313, 54

SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCNCC1

InChI Key InChIKey=IDRHKJAGRANANS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50257664   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50257664(US8569313, 54 | CHEMBL493118 | (S)-3-amino-N-(3-(N...)
Affinity DataKi:  36nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50257664(US8569313, 54 | CHEMBL493118 | (S)-3-amino-N-(3-(N...)
Affinity DataKi:  37nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664(US8569313, 54 | CHEMBL493118 | (S)-3-amino-N-(3-(N...)
Affinity DataKi:  880nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664(US8569313, 54 | CHEMBL493118 | (S)-3-amino-N-(3-(N...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664(US8569313, 54 | CHEMBL493118 | (S)-3-amino-N-(3-(N...)
Affinity DataKi:  2.56E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664(US8569313, 54 | CHEMBL493118 | (S)-3-amino-N-(3-(N...)
Affinity DataKi:  7.17E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed