BDBM50257719 (S)-N-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4-yl)tetrahydrofuran-2-carboxamide::CHEMBL493752

SMILES Nc1ccnc(c1)N1CCC(CC1)(NC(=O)[C@@H]1CCCO1)c1ccccc1

InChI Key InChIKey=GVOROESSOVMDMF-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257719   

TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257719((S)-N-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4...)
Affinity DataEC50:  171nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by ALPHAscreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50257719((S)-N-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed