BDBM50257723 2-(3-phenyl-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)pyridin-4-amine::CHEMBL492553

SMILES Nc1ccnc(c1)N1CCC2(CC1)OC(c1ccccc21)c1ccccc1

InChI Key InChIKey=NPAADSKMLSZJIV-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257723   

LigandPNGBDBM50257723(2-(3-phenyl-3H-spiro[isobenzofuran-1,4'-piperidine...)
Affinity DataKi:  18nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257723(2-(3-phenyl-3H-spiro[isobenzofuran-1,4'-piperidine...)
Affinity DataEC50:  59nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by ALPHAscreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed