BDBM50258513 3-(2-chloro-4-((5-cyclobutyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL468110

SMILES OC(=O)c1cccc(\C=C\c2ccc(OCc3c(noc3C3CCC3)-c3c(Cl)cccc3Cl)cc2Cl)c1

InChI Key InChIKey=HQCOQYGJAPTGIE-ZHACJKMWSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258513   

TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258513(3-(2-chloro-4-((5-cyclobutyl-3-(2,6-dichlorophenyl...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258513(3-(2-chloro-4-((5-cyclobutyl-3-(2,6-dichlorophenyl...)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed