BDBM50258645 CHEMBL511212::N1-hydroxy-N8-(4-phenylthiazol-2-yl)octanediamide

SMILES ONC(=O)CCCCCCC(=O)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=BDTAPZUZFJRPNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258645   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258645(N1-hydroxy-N8-(4-phenylthiazol-2-yl)octanediamide ...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258645(N1-hydroxy-N8-(4-phenylthiazol-2-yl)octanediamide ...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258645(N1-hydroxy-N8-(4-phenylthiazol-2-yl)octanediamide ...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed