BDBM50258649 5-(5-(4-(3-aminophenyl)thiazol-2-ylamino)-5-oxopentyl)-N-hydroxyisoxazole-3-carboxamide::CHEMBL511432

SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCc2cc(no2)C(=O)NO)n1

InChI Key InChIKey=VEZHOKIXUARAOE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258649   

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258649(5-(5-(4-(3-aminophenyl)thiazol-2-ylamino)-5-oxopen...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258649(5-(5-(4-(3-aminophenyl)thiazol-2-ylamino)-5-oxopen...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258649(5-(5-(4-(3-aminophenyl)thiazol-2-ylamino)-5-oxopen...)
Affinity DataIC50: 139nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258649(5-(5-(4-(3-aminophenyl)thiazol-2-ylamino)-5-oxopen...)
Affinity DataIC50: 164nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258649(5-(5-(4-(3-aminophenyl)thiazol-2-ylamino)-5-oxopen...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed