BDBM50258710 3-(2-chloro-4-((5-isopropyl-3-(3-phenylpropyl)isoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL467060

SMILES CC(C)c1onc(CCCc2ccccc2)c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=XXYLNCPQPFZEFG-CCEZHUSRSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258710   

TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258710(3-(2-chloro-4-((5-isopropyl-3-(3-phenylpropyl)isox...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258710(3-(2-chloro-4-((5-isopropyl-3-(3-phenylpropyl)isox...)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed