BDBM50258746 3-(2-chloro-4-((3-((2,6-dichlorophenylamino)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL466452

SMILES CC(C)c1onc(CNc2c(Cl)cccc2Cl)c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=FIEQTERVDPPZLJ-MDZDMXLPSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258746   

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258746(3-(2-chloro-4-((3-((2,6-dichlorophenylamino)methyl...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258746(3-(2-chloro-4-((3-((2,6-dichlorophenylamino)methyl...)
Affinity DataEC50:  72nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed