BDBM50258847 4-(1-(4-methoxyphenyl)cyclopentyl)thiazol-2-amine::CHEMBL449357

SMILES COc1ccc(cc1)C1(CCCC1)c1csc(N)n1

InChI Key InChIKey=CKMNYFMEILPBLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258847   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258847(4-(1-(4-methoxyphenyl)cyclopentyl)thiazol-2-amine ...)
Affinity DataIC50: 2.50E+4nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed