BDBM50258849 4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)ethyl)thiazol-2-amine::CHEMBL466025

SMILES COc1ccc(cc1)C(Cc1cc(ccc1OC)[N+]([O-])=O)c1csc(N)n1

InChI Key InChIKey=PBSYABIBXNOMBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258849   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258849(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 1.10E+3nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258849(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 2.20E+7nMAssay Description:Inhibition of BACE1 by sAPP_NF cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed