BDBM50258894 CHEMBL4067117

SMILES COCC(NC(=O)N1CC(=O)Nc2cc(OC)cnc12)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=OGWMIGNXKNAVSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258894   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258894(CHEMBL4067117)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2019
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258894(CHEMBL4067117)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2019
Entry Details Article
PubMed