BDBM50259090 CHEMBL466314::benzyl 3-(3-chloro-4-fluorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-ylcarbamate

SMILES Fc1ccc(Cn2cnc3ccc(NC(=O)OCc4ccccc4)cc3c2=O)cc1Cl

InChI Key InChIKey=LDXYQWNHOVBYJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259090   

TargetStearoyl-CoA desaturase(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259090(benzyl 3-(3-chloro-4-fluorobenzyl)-4-oxo-3,4-dihyd...)
Affinity DataIC50: 220nMAssay Description:Inhibition of delta-(9)-desaturase from human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259090(benzyl 3-(3-chloro-4-fluorobenzyl)-4-oxo-3,4-dihyd...)
Affinity DataIC50: 865nMAssay Description:Inhibition of rat microsomal delta-(9)-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed