BDBM50259098 CHEMBL3084526::endo-8-(bis(2-chlorophenyl)methyl)-3-(4-fluorobenzyl)-8-azabicyclo[3.2.1]octane-3-carboxamide

SMILES [H][C@]12CC[C@]([H])(C[C@@](Cc3ccc(F)cc3)(C1)C(N)=O)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=SPEHUFZCQVFXFF-NHCUHLMSSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259098   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259098(CHEMBL3084526 | endo-8-(bis(2-chlorophenyl)methyl)...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259098(CHEMBL3084526 | endo-8-(bis(2-chlorophenyl)methyl)...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259098(CHEMBL3084526 | endo-8-(bis(2-chlorophenyl)methyl)...)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259098(CHEMBL3084526 | endo-8-(bis(2-chlorophenyl)methyl)...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed