BDBM50259142 CHEMBL3084529::endo-8-(bis(2-chlorophenyl)methyl)-3-(5-fluoropyridin-2-yl)-8-azabicyclo[3.2.1]octane-3-carboxamide
SMILES [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1ccc(F)cn1)N2C(c1ccccc1Cl)c1ccccc1Cl
InChI Key InChIKey=BZGMTXHQYFWFDV-QZTJIDSGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50259142
Affinity DataKi: 7nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 123nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.61E+3nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 3.35E+3nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataEC50: 733nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair