BDBM50259337 3-((7-(2-chlorophenyl)-6-(4-chlorophenyl)-2-isopropylpyrido[2,3-d]pyrimidin-4-yloxy)methyl)-1,2,4-oxadiazole::CHEMBL466110

SMILES CC(C)c1nc(OCc2ncon2)c2cc(-c3ccc(Cl)cc3)c(nc2n1)-c1ccccc1Cl

InChI Key InChIKey=MAKUUSXZRYVVJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259337   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259337(3-((7-(2-chlorophenyl)-6-(4-chlorophenyl)-2-isopro...)
Affinity DataIC50: 1.10nMAssay Description:Inverse agonist activity at human cannabinoid CB1R expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259337(3-((7-(2-chlorophenyl)-6-(4-chlorophenyl)-2-isopro...)
Affinity DataIC50: 6.30E+3nMAssay Description:Binding affinity to human cannabinoid CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed