BDBM50259419 (1R,5S)-7-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}-3-phenylmethanesulfonyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid(2-chloro-benzyl)-methyl-amide::CHEMBL508748

SMILES COc1ccccc1COCCCOc1ccc(cc1)C1=C([C@H]2CN(C[C@@H](C1)N2)S(=O)(=O)Cc1ccccc1)C(=O)N(C)Cc1ccccc1Cl

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259419   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259419((1R,5S)-7-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phe...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259419((1R,5S)-7-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phe...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed