BDBM50259424 (1R,5S)-3-Acetyl-7-{4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl}-3,9-diaza-bicyclo[3.3.1]non-6-ene-6-carboxylic acid 2-chloro-benzylamide::CHEMBL455047

SMILES COc1ccccc1COCCCOc1ccc(C2=C(C(=O)NCc3ccccc3Cl)[C@H]3CN(C(C)=O)C[C@@H](C2)N3)cc1

InChI Key InChIKey=YMOHKWJTFCXWAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259424   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259424BDBM50259424((1R,5S)-3-Acetyl-7-{4-[3-(2-methoxy-benzyloxy)-pro...)
Affinity DataIC50: 116nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259424BDBM50259424((1R,5S)-3-Acetyl-7-{4-[3-(2-methoxy-benzyloxy)-pro...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed