BDBM50259425 (1R,5S)-3-Acetyl-7-{4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl}-3,9-diaza-bicyclo[3.3.1]non-6-ene-6-carboxylic acid benzyl-methyl-amide::CHEMBL505760

SMILES COc1ccccc1COCCCOc1ccc(C2=C(C(=O)N(C)Cc3ccccc3)[C@H]3CN(C(C)=O)C[C@@H](C2)N3)cc1

InChI Key InChIKey=YCHCQQAZGGXUFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259425   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259425BDBM50259425((1R,5S)-3-Acetyl-7-{4-[3-(2-methoxy-benzyloxy)-pro...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259425BDBM50259425((1R,5S)-3-Acetyl-7-{4-[3-(2-methoxy-benzyloxy)-pro...)
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed