BDBM50259461 (1R,5S)-7-{2-[2-(2,6-Dichloro-4-methyl-phenoxy)-ethoxy]-thiazol-5-yl}-3,9-diaza-bicyclo[3.3.1]-non-6-ene-6-carboxylic acid cyclopropyl-(2,3-dimethyl-benzyl)-amide::CHEMBL505635

SMILES Cc1cc(Cl)c(OCCOc2ncc(s2)C2=C([C@H]3CNC[C@@H](C2)N3)C(=O)N(Cc2cccc(C)c2C)C2CC2)c(Cl)c1

InChI Key InChIKey=OFUSFLWUWUMATA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259461   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259461((1R,5S)-7-{2-[2-(2,6-Dichloro-4-methyl-phenoxy)-et...)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259461((1R,5S)-7-{2-[2-(2,6-Dichloro-4-methyl-phenoxy)-et...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed