BDBM50259499 (1S,9R,10R,11R)-12-[4-(4-Chloro-phenyl)-5-phenyl-thiazol-2-yl]-10-hydroxymethyl-6-oxo-7,12-diaza-tricyclo[7.2.1.0*2,7*]dodeca-2,4-diene-11-carboxylicacid (3-pyrrolidin-1-yl-propyl)-amide::CHEMBL501763

SMILES OC[C@H]1[C@@H]2Cn3c(cccc3=O)[C@H]([C@@H]1C(=O)NCCCN1CCCC1)N2c1nc(c(s1)-c1ccccc1)-c1ccc(Cl)cc1

InChI Key InChIKey=FRVRETVPMVMMPI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259499   

TargetApoptosis regulator Bcl-2(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259499((1S,9R,10R,11R)-12-[4-(4-Chloro-phenyl)-5-phenyl-t...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of fluorescently-tagged BH3 peptide from Bcl-2 by chemiluminescent nitrogen detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259499((1S,9R,10R,11R)-12-[4-(4-Chloro-phenyl)-5-phenyl-t...)
Affinity DataKi:  5.70E+3nMAssay Description:Displacement of fluorescently-tagged BH3 peptide from Bcl-XL by chemiluminescent nitrogen detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed