BDBM50259575 (R)-3-methyl-2-(4'-((4-(pyridin-2-yloxy)phenoxy)methyl)biphenyl-4-ylsulfonamido)butanoic acid::CHEMBL512804

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(COc2ccc(Oc3ccccn3)cc2)cc1)C(O)=O

InChI Key InChIKey=GHQXFUXFILXMCE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259575   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50259575((R)-3-methyl-2-(4'-((4-(pyridin-2-yloxy)phenoxy)me...)Copy SMILESCopy InChI

Affinity DataIC50: 900nMAssay Description:Inhibition of aggrecanase1More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
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