BDBM50259969 CHEMBL4104527

SMILES CN(Cc1cc(c(F)cc1F)[C@]1(C)CCSC(N)=N1)CC(F)(F)F

InChI Key InChIKey=RHXHFXVYZBDQQN-AWEZNQCLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259969   

TargetBeta-secretase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50259969(CHEMBL4104527)
Affinity DataIC50: >8.40E+4nMAssay Description:Inhibition of BACE2 (unknown origin) by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50259969(CHEMBL4104527)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of BACE1 in human H4 cells expressing wild type APP695 assessed as reduction in soluble APPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50259969(CHEMBL4104527)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Cathepsin D (unknown origin) by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50259969(CHEMBL4104527)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed