BDBM50260361 CHEMBL4066170

SMILES COc1cc(N(C)CC[N+](C)(C)[O-])c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccc(F)cc12

InChI Key InChIKey=MTILPOMEZWINDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260361   

TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260361(CHEMBL4066170)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260361(CHEMBL4066170)
Affinity DataIC50: 357nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed