BDBM50260469 CHEMBL4091214

SMILES CN1C=CC(C=C1)C1OC(=CN1c1ccc(cc1)S(N)(=O)=O)C(Cl)(Cl)Cl

InChI Key InChIKey=SEPDPSPSAHPGQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260469   

TargetProstaglandin G/H synthase 2(Rat)
Chongqing Normal University

Curated by ChEMBL
LigandPNGBDBM50260469(CHEMBL4091214)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rat)
Chongqing Normal University

Curated by ChEMBL
LigandPNGBDBM50260469(CHEMBL4091214)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of COX-1 in rat peritoneal macrophages assessed as reduction in [125I]-6-Keto-PGF1alpha production using arachidonic acid as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed