BDBM50260888 3-(2-aminoquinazolin-6-yl)-1-(2-cyclopentylethyl)-4-methylpyridin-2(1H)-one::CHEMBL494821

SMILES Cc1ccn(CCC2CCCC2)c(=O)c1-c1ccc2nc(N)ncc2c1

InChI Key InChIKey=UGOPZRICVJBSEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260888   

LigandPNGBDBM50260888(3-(2-aminoquinazolin-6-yl)-1-(2-cyclopentylethyl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Kit by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50260888(3-(2-aminoquinazolin-6-yl)-1-(2-cyclopentylethyl)-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of Lck by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50260888(3-(2-aminoquinazolin-6-yl)-1-(2-cyclopentylethyl)-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50260888(3-(2-aminoquinazolin-6-yl)-1-(2-cyclopentylethyl)-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed