BDBM50260922 CHEMBL4060747

SMILES Cc1ccc(cc1)-c1cnc(N)c(c1)-c1nnc(o1)C1CC1

InChI Key InChIKey=ULNLCNDIUOYPMB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260922   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50260922(CHEMBL4060747)Copy SMILESCopy InChI

Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human LRRK2 (970 to 2527 residues) G2019S mutant expressed in baculovirus preincubated for 30 mins followed by fluorescein-...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/16/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50260922(CHEMBL4060747)Copy SMILESCopy InChI

Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL